Coastguard helicopters are circling the River Orwell in Ipswich in search for missing man Edward Osborne.
Mr Osborne, 43, from Framlingham, was last heard from about 5.30pm on Tuesday and was reported missing later in the evening.
It is believed that Mr Osborne is driving his car, a blue Skoda with the registration CX11 ZBP.
He is described as white, about 6ft tall with a slim build. Mr Osborne has a large tattoo of a raven bird on his upper right arm.
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He is believed to be wearing a blue padded coat, a black hoody with orange writing on the front, blue jeans, black and white converse-style trainers and a black woollen hat.
Officers are carrying out searches around the River Orwell in Ipswich and surrounding coastline and believe he may be in the Ipswich area.
Coastguard and Suffolk Lowland Search and Rescue are assisting with the search.
Mr Osborne's family and officers are very concerned for his welfare and are asking anyone who may have seen him, or know of his current whereabouts, to call police on 999 quoting CAD 361 of Tuesday, January 14.
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